Collaborative Research Center (SFB) 677 - Function by Switching

C13: Switching in molecular double layer membranes (since 2015)


Amphiphilic photoswitchable molocules will be integrated into phospholipid membranes in order to investigate their biologically relevant properties. By studying the interactions in such a model system consisting of switchable biomimetic molecules in lipid membranes here, we will obtain experimental data to help explain the structure and kinetics of .the switching process. Changes in membrane conformation upon photoswitching will be investigated by X-ray scattering methods allowing molecular resolution. These experiments not only contribute to the fundamental understanding of membrane dynamics but will contribute to potential applications for molecular switches such as drug delivery.

Project Graphical Abstract